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Tablets

At IHR, we offer customers a huge range of ayurvedic products in tablet dosage form with unparalleled finish one can find in entire India. We use the best compression machines and new die-punches to make smooth tablets that pass every test of stability, disintegration and dissolution.

Tablets are unit, solid dosage forms, containing one or more active ingredients for oral administration. Tablets also contain additives like binders, diluents, disintegrating agent lubricants, glidents and other material for coating of tablets. Some material to form complex with active ingredients for controlled release of active ingredients after administration are also added in formulations. Organoleptic agents like, Permitted colouring, Flavouring and Sweetening agents are also added where ever required. Tablets are swallowed whole with water, milk or other suitable liquids, some are chewed and swallowed, some are dissolved or dispersed in water before administration and some are retained in mouth release of drug.

The range of Tablets we offer are as follows :

1) Core Tablets or Uncoated Tablets: These are single or double layer, uncoated tablets are compressed tablets. No other treatment is applied to such tablets. The addition of colouring or flavouring agents to uncoated tablets other than multilayer tablets is not official unless permitted in the individual monograph of Official Books and Pharmacopoeias.

2) Coated Tablets: One or more layer of mixture of various substances such as, resin, gum and insoluble fillers, sugars, plasticizers, polyhydric alcohols, waxes etc. are applied to the core tablets. Some special cases coating may also contain active ingredients.

Film Coated Tablets: When the coating is thin the tablets are described as film-coated.
Sugar Coated Tablets: When sugar solutions with other additives are used for coating. Coating is called as sugar coating.

Coated tablets may contain flavouring and or one or more permitted colouring agents.Coated tablets have a smooth, usually polished and often coloured surface. A broken section examined under a lens shows a core surrounded one or continuous layer of a different texture.

3) Enteric Coated Tablets: Enteric coated tablets are tablets covered with one or more layers of coating intended to resist the gastric fluid but to release their active ingredients in the intestinal fluid. For this CAP (Cellulose Acetate Phthalate) and anionic copolymers of methacrylic acid and its ethers are used for providing tablets with a gastric resistant coating.

4) Dispersible Tablets: Dispersible tablets are uncoated tablets that produce a uniform dispersion in water and may contain permitted colouring and flavouring agents.

5) Modified Release Tablets: These are sustained release, coated, uncoated tablets containing other additives and prepared by procedure that, separately or together, are designed to modify the rate or the place at which the active drug is released.

6) Soluble Tablets: These are uncoated tablets that are dissolved in water.

7) Effervescent Tablets: These are uncoated tablets generally containing acidic substances and either carbonate or bicarbonates which react rapidly in the presence of water to release carbon-di-oxide. They are dissolved or dispersed in water before administration.

We offer the following Testing Parameters for Tablets.

1. Disintegration:

a) Uncoated Tablets: Tablets should disintegrate within 15 minutes by using water as medium.
b) Film Coated Tablets: Tablets should disintegrate within 30 minutes by using water as medium and adding disc to each tube. (Water Temperature.37°± 2°C)
c) Other Coated Tablets: Tablet should disintegrate within 60 minutes by using water is medium and adding disc to each tube. (Water Temperature.37°± 2°C)
d) Enteric Coated Tablets: Tablets should not shows sign of disintegration for 120 minutes in Acidic Medium (0.1m hydrochloric acid) without disc and tablets should disintegration within 60 minutes in mixed phosphate buffer medium (pH6.8) with addition of disc.(Temperature.37°± 2°C).
e) Dispersible and Soluble Tablets: Disintegrate within 3 minutes using water as medium at 24 to 26°C temperature.
f) Effervescent Tablets: Limit – within 5 minutes in Beaker containing water at 20 to 30°C.

2. Dissolution Test: Testing stages and Acceptance limits as per IP 1996:

3. Hardness Test: Limit not less than 4 kg per cm.sq.

4. Friability Test: Limit not more than 2% by using friabilator.

 

 Below is a sample of DS Die ( upto 700 mg ) Tablet.